Pdf classification of systemic lupus erythematosus. Criteria are cumulative and need not be present concurrently. The new systemic lupus international collaborating clinics slicc 2012 classification criteria aimed to improve the performance of. Lupus is a chronic inflammatory autoimmune disease with a wide range of clinical presentations resulting from its effect. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. Therapeutic opportunities in systemic lupus erythematosus. An overview of the disease and management options ncbi.
Reprinted with permission from bertsias gk, salmon je, boumpas dt. Systemic lupus erythematosus sle is the prototypic multisystem autoimmune disorder with a broad spectrum. Ocular manifestations of systemic lupus erythematosus. Slicc, systemic lupus international collaborating clinicsamerican college of rheumatology damage index. Figure 1 natural history of systemic lupus erythematosus. Pdf systemic lupus erythematosus sle is the prototype of autoimmune diseases with multiple autoantigens as. Its diversity of clinical features is matched by the complexity of the factors genetic, hormonal, and environmental that cause it, and the array of autoantibodies with which it is associated.
The four main types of lupus are neonatal and pediatric lupus erythematosus nle. Systemic lupus erythematosus sle, is the most common type of lupus. This book provides a comprehensive overview of the basic and clinical sciences of systemic lupus erythematosus. Classification criteria for systemic lupus erythematosus. Harrison principles of internal medicine 18th edition. Diet and nutritional aspects in systemic lupus erythematosus scielo. Isbn 9789535102663, pdf isbn 9789535168928, published 2012 0321. Lupus is a chronic inflammatory autoimmune disease with a wide range of clinical presentations resulting from its effect on multiple organ systems. Systemic lupus erythematosus sle is the prototype of autoimmune diseases with multiple. Systemic lupus erythematosus sle is a multisystemic chronic inflammatory disease of unknown cause and. Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus. Sle is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. Systemic lupus erythematosus larissa lisnevskaia, grainne murphy, david isenberg systemic lupus erythematosus is a remarkable and challenging disorder. It is suitable for basic scientists looking for detailed coverage of their areas of interest.
Petri m, orbai am, alarcon gs, gordon c, merrill jt, et al. Systemic lupus erythematosus, mechanisms of disease. American college of rheumatology guidelines for screening, treatment, and management of lupus nephritis bevra h. Systemic lupus erythematosus is a systemic autoimmune disease with a worldwide distribution. Derivation and validation of the systemic lupus erythematosus. Derivation and validation of the systemic lupus international collaborating clinics classi. About onethird of patients suffering from systemic lupus erythematosus have. Cutaneous manifestations of systemic lupus erythematosus hindawi.
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